Cleveland Clinic and Khosla Ventures announced a strategic collaboration that connects the international health system with one of Silicon Valley’s leading investors in healthcare and technology.

The new relationship combines the organizations’ unique strengths, aiming to reimagine healthcare delivery and create solutions that address some of the most pressing challenges in the field.

As part of the collaboration, Khosla Ventures portfolio companies can work with Cleveland Clinic providers to showcase and test new technologies at all stages — from clinical validation to commercial adoption. This access gives startups a distinct advantage to demonstrate value directly with clinicians, accelerating the journey from early, bold ideas to proven, scalable solutions.

For Cleveland Clinic, the collaboration provides a direct pipeline to emerging technologies in areas such as artificial intelligence, digital health, and next-generation therapeutics.

“Khosla Ventures invests in early, bold, and impactful ideas that help people get healthy, stay healthy, and live longer,” said Hal Paz, MD, operating partner at Khosla Ventures and former CEO of multiple large-scale health systems. “AI is the most transformative technology of our lifetime, and its impact on healthcare will be massive. This relationship with Cleveland Clinic — one of the most respected health institutions in the world — gives our companies an advantage to validate and scale their innovations.”

“This collaboration pairs our health system’s expertise in biomedical research, clinical care and innovation with Khosla Ventures’ venture expertise and network of entrepreneurs to drive meaningful advancements in the healthcare industry,” said Geoff Vince, PhD, Chief, Cleveland Clinic Innovations. “Together we aim to accelerate transformational innovation, foster groundbreaking technologies, and ultimately improve patient outcomes.”