Global Fund & Siemens Healthineers Boost Artificial Intelligence for Tuberculosis Diagnosis

• Tuberculosis is once again the leading infectious disease killer globally. 
• AI-based X-ray screening enables early detection and management of the disease and diagnoses “missing” patients. 

The two organizations will work together to speed up the adoption of AI in chest X-rays to improve efficiency and accuracy. With AI, routine scans can be read more quickly, so more people can be screened for TB, and cases of TB that went previously undetected can be diagnosed. One person with active, untreated TB can spread the disease to as many as 15 other people in a year, so early detection is key. 

“Patient finding and diagnosis continue to be key obstacles in the fight against tuberculosis,” said Peter Sands, Executive Director of the Global Fund. “Every year, we estimate that millions of people with TB are missing from the radar. If we are to beat this disease, which still kills one person every two minutes, we urgently need more efficient and more accurate tools to detect it. We believe that AI is one of the answers.” 

The partnership will initially focus on Indonesia, which has one of the highest TB burdens in the world, accounting for more than 9% of global cases, and where less than half of infected people get treatment. Siemens Healthineers, working closely with Qure.AI, a company using deep-learning technology to automate the interpretation of radiology exams, will provide free licenses and train health care workers as AI processes are rolled into their workflows. AI will also enable trained radiologists who are not on-site to read scans, bringing screening to remote areas not previously covered. 

Siemens Healthineers, a leading medical technology company, is committed to finding ways to bring quality health care to everyone, no matter where they live. 

“We continue to push technology to find innovative tools for diagnosis,” said Siemens Healthineers Chief Executive Bernd Montag. “A century ago, it was fitting massive X-ray machines into buses for mobile screening. Today, we harness expertise in AI to supercharge screening programs for more precise, earlier TB diagnosis for a greater number of people.” 

The Global Fund provides the largest share – 76% – of all international financing for TB. In countries where the Global Fund invests, TB deaths (excluding people living with HIV) reduced by 16% between 2002 and 2021. In 2022, TB programs accelerated their recovery, not only erasing the losses of 2020 but exceeding the pre-COVID-19 results of 2019. Compared to 2021, The Global Fund registered an increase of 1.4 million more people diagnosed and treated. Innovations – such as integrating screening for TB alongside other diseases, and new treatments including for drug-resistant TB – are boosting progress. 

The Global Fund’s 2021-2023 TB grants of up to a combined US$157 million continue to support focused interventions designed to end the TB epidemic in Indonesia.