Longhorn Vaccines and Diagnostics, in collaboration with the National Institutes of Health’s NIAID, has validated its PrimeStore® Molecular Transport Medium (MTM) as an effective tool for inactivating a range of high-risk pathogens. The study, published in Viruses, confirmed PrimeStore MTM’s ability to neutralize viruses including Ebola, Marburg, Lassa, Nipah, and West Nile, demonstrating its utility in improving biosafety during sample collection and processing. This positions PrimeStore MTM as a reliable solution for diagnostics in both clinical and field environments, particularly during outbreaks involving dangerous pathogens.

What sets PrimeStore MTM apart is its FDA clearance as the only molecular transport medium approved for inactivating both DNA and RNA viruses, while also preserving nucleic acids for downstream molecular testing. The medium works at ambient temperature, reducing the need for cold-chain logistics and minimizing the risk of laboratory-acquired infections. NIAID's rigorous testing showed that the medium effectively inactivated all ten targeted pathogens at high concentrations, reinforcing its robustness and safety in real-world diagnostic workflows.

This study’s conclusion highlights PrimeStore MTM as a game-changing tool for global infectious disease control, capable of enhancing laboratory safety, simplifying diagnostic logistics, and improving cost efficiency. As emphasized by Longhorn executives, the technology plays a critical role in protecting laboratory personnel and ensuring accurate, timely diagnosis of zoonotic and emerging infectious diseases. The results support its broader adoption in public health initiatives and outbreak preparedness strategies worldwide.

MedTech Spectrum's Summary

Proven Pathogen Inactivation: A collaborative study with the NIH’s NIAID confirmed that Longhorn’s PrimeStore® MTM effectively inactivates ten high-consequence pathogens, including Ebola, Lassa, and Nipah viruses, significantly enhancing safety during sample collection, transport, and testing.

FDA-Cleared and Field-Ready: PrimeStore MTM is the only FDA-cleared molecular transport medium that inactivates both DNA and RNA viruses while preserving nucleic acids at ambient temperatures, simplifying workflows and eliminating the need for cold-chain logistics.

Critical Tool for Global Health: The study validates PrimeStore MTM as a vital solution for biosafety and outbreak response, making it an essential component in diagnostic labs, field surveillance, and pandemic preparedness efforts.