Stryker’s Inari Medical Introduces Artix Thrombectomy System to Enhance Arterial Clot Removal

Inari Medical, now part of Stryker a global leader in medical technologies, announced the launch of its Artix Thrombectomy System. Purpose-built for the distinct needs of the peripheral arterial system, Artix is a combined aspiration plus mechanical thrombectomy solution that delivers procedural control and versatility, and is designed to set a new standard for arterial thrombectomy.

An arterial blood clot in the leg is a life- and limb-threatening emergency requiring immediate treatment. However, existing therapies for arterial thromboembolism can lead to:

• Ineffective clot retrieval leading to additional procedures (open surgery or amputation)
• Significant blood loss
• Adverse events such as arterial embolization and vessel trauma
• High rates of lytic use, which may result in complications

The Artix System builds on the success of Inari's venous thrombectomy devices and is its inaugural entry into the arterial space. Inari offers a comprehensive toolkit approach to arterial thrombectomy with an innovative, over-the-wire system that provides physicians with the flexibility to aspirate and/or mechanically extract a clot.

Jonathan Bowman, MD FACS, Chief of Vascular at Norwalk Hospital in Norwalk, CT, performed the first commercial case with Artix on October 19, 2024. "The Artix Thrombectomy System marks a significant advancement in peripheral arterial thromboembolism treatment," said Dr. Bowman. "With Artix, I finally have a solution that effectively addresses a wide range of clots while enabling me to maintain vessel access and retain control throughout the entire case. I expect Artix will take the place of open surgical repair in many of my arterial cases."

Key distinctive features of the Artix system include:

• Dual mechanical thrombectomy and aspiration toolkit designed to remove acute to chronic clots in a single session via a streamlined procedure⁴
• Aspiration-capable, 8 Fr. low profile, trackable, kink-resistant sheath in both 65cm and 90cm lengths expands treatment options by enabling more complex and distal interventions
• Innovative over-the-wire mechanical element designed to effectively collect and retrieve acute-to-chronic clot⁴
• Covered nitinol mesh funnel provides temporary flow restriction during the procedure to minimize the risk of arterial clot migration⁵

"There is a real clinical need to address chronic thrombi and decrease the risk of clot migration. Artix will raise the bar of effective arterial thrombectomy," said Tom Tu, MD, Chief Medical Officer of Inari Medical. "We are excited to bring Inari's core competency in thrombectomy to the arterial space with the goal of improving outcomes."